A fork of Rural Dictionary
To talk someone down is to speak to them in a soothing voice in an attempt to calm them down, especially when they're vomit-drunk or having a bad trip. This usually takes place behind or next to the person having a bad trip, in front of a bathroom mirror in a stranger's house while your best friend is curled up in a ball in the bathtub and someone already has the toilet.
I wanted to roll over and die after the third hit, but thanks to Derek talking me down I was okay. She should be alright after a good talk down.