A fork of Rural Dictionary
A University of athletic excellence in upstate New York.
CUSE is in the house, OH MY GOD
the ultimate burn ... burn to the MAX
dude, he shizzled your nizzle, thats a top dawg CUSE
The city of Syracuse, New York.
Nick name used by Syracuse natives when referencing their hometown and/or Syracuse University.
Did you watch the Cuse game last night?
Familiar, endearing name for Syracuse, NY. Used by people of Upstate, New York.
It's snowing in Cuse again.