A fork of Rural Dictionary
Short for Home Depot. Depo is the highest insult to a person's intelligence that one can make, above Hardware store, Toolshed, Toolbox, and Tool.
Bob: Billy still uses Internet Explorer. Joe: We've always thought he was a Depo, this is just the final nail in his coffin.
Depo-Provera. A birth control solution given as a shot. Contains synthesized hormones similar to those in convential birth control pills. Administered as a shot every few months to prevent ovulation.
I asked my girlfriend to start getting depo shots because I didn't want her to get pregnant by my good for nothing sperm.
A unit of measure for compensation in a sugar daddy/sugar baby relationship. His average DEPO with his girl is $500.